A Disease

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A Treatment

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A Treatment 2

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A Treatment 3

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Ask the Expert

“Ask the Expert” is a free question-and-answer event sponsored by RI Brain & Spine Tumor Foundation (“RIBSTF”) in an effort to assist and educate patients, caregivers and families that are dealing with a brain or spine tumor diagnosis.

Our panel of “experts” are specialists representing a comprehensive care team a patient would encounter in their journey with this diagnosis. The event includes experts in the following fields: Neurosurgery, Neuro-Oncology, Neuro-Rehab, Neuro Radiology, Pathology, Radiation Oncology, Care Coordination and Hospice Services. Also, come and meet Andrew Reis, a brain tumor survivor.

For more information, please call (401) 272-4177

What:  Ask the expert event

When:  Saturday, January 28, 2012

Where:  Bethany Home of RI – 111 South Angell Street, Providence, RI
For directions visit: www.bethanyhomeofri.org

Time: 10am till 12pm  

List of Experts by Specialty:

Neurosurgery: Charles Kanaly, MD (RI Neurosurgical)
Neuro-oncology: Suriya Jeyapalan, MD
Neuro-rehab: Jon Mukand, MD
Pathology: Edward Stopa, MD
Neuro-radiology: Jerrold Boxerman, MD (RI Medical Imaging)
Radiation Oncology: Tim Shafman, MD (21st Century Oncology)
Oncology Nursing: Xristin Maestri, RNP
Social Work: Diane Passantino (RIH Cancer Center)
Hospice Services: Marybeth Quinn, RN (Odyssey Healthcare)
Patient/Survivor: Andrew Reis

 View the event information.

Ask the Experts

“Ask the Experts” is a free question-and-answer event sponsored by RI Brain & Spine Tumor Foundation (“RIBSTF”) in an effort to assist and educate patients, caregivers and families that are dealing with a brain or spine tumor diagnosis.

Our panel of “experts” are specialists representing a comprehensive care team a patient would encounter in their journey with this diagnosis. The event includes experts in the following fields: Neurosurgery, Neuro-Oncology, Pathology, and Care Coordination. Also, come and meet Andrew Reis, a brain tumor survivor.

For more information, please call (401) 272-4177

What: Ask the experts event

When:  Saturday, September 29, 2012

Where: South County Hospital “Potter’s Conference” – 100 Kenyon Ave, Wakefield, RI 02879

Time: 10am till 12pm  

List of Experts by Specialty:

Neurosurgery:  Prakash Sampath, MD (RI Neurosurgical), G. Rees Cosgrove, MD (Neurosurgery Foundation) Neuro-oncology: Suriya Jeyapalan, MD Pathology: Scott Wang, MD Patient/Survivor: Andrew Reis

B Disease

Lorem Ipsum is simply dummy text of the printing and typesetting industry. Lorem Ipsum has been the industry’s standard dummy text ever since the 1500s, when an unknown printer took a galley of type and scrambled it to make a type specimen book. It has survived not only five centuries, but also the leap into electronic typesetting, remaining essentially unchanged. It was popularised in the 1960s with the release of Letraset sheets containing Lorem Ipsum passages, and more recently with desktop publishing software like Aldus PageMaker including versions of Lorem Ipsum.

B Treatment

Lorem ipsum dolor sit amet, consectetur adipisicing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur. Excepteur sint occaecat cupidatat non proident, sunt in culpa qui officia deserunt mollit anim id est laborum.

Lorem ipsum dolor sit amet, consectetur adipisicing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur. Excepteur sint occaecat cupidatat non proident, sunt in culpa qui officia deserunt mollit anim id est laborum.

Clinical Applications of a Peptide-Based Vaccine for Glioblastoma

Glioblastoma multiforme (GBM) is a malignant, relentless brain cancer with no known cure, and standard therapies leave significant room for the development of better, more effective treatments. Immunotherapy is a promising approach to the treatment of solid tumors that directs the patient’s own immune system to destroy tumor cells. The most widespread and successful immunologically-based cancer therapy to date involves the passive administration of monoclonal antibodies, but significant antitumor responses have also been generated with active vaccination strategies and cell-transfer therapies as well. This article summarizes the important components of the immune system, discusses the specific difficulty of immunologic privilege in the central nervous system (CNS), and reviews the variety of treatment approaches that are being attempted, with an emphasis on active immunotherapy using peptide vaccines in the treatment of GBM… [Read the rest of the publication]

D Disease

Lorem Ipsum is simply dummy text of the printing and typesetting industry. Lorem Ipsum has been the industry’s standard dummy text ever since the 1500s, when an unknown printer took a galley of type and scrambled it to make a type specimen book. It has survived not only five centuries, but also the leap into electronic typesetting, remaining essentially unchanged. It was popularised in the 1960s with the release of Letraset sheets containing Lorem Ipsum passages, and more recently with desktop publishing software like Aldus PageMaker including versions of Lorem Ipsum.

Dr. Charles Kanaly Gives Invited Lecture on Brain Tumors for Medical Grand Rounds

Dr. Kanaly was the invited speaker for Medical Grand Rounds at Roger Williams Medical Center in Providence, RI on Tuesday, February 19, 2013.  His lecture was entitled “CNS Malignancies: A Surgical Perspective.”

Dr. Charles Kanaly is Featured in The Page Newsletter of Memorial Hospital of Rhode Island

Dr. Charles Kanaly wrote an article in the Memorial Hospital patient newsletter on January 25, 2013.  In the article, he explains when patients should seek medical evaluation of low back pain and also common treatments that are offered.  The entire article can be read by clicking here.

Dr. Charles Kanaly is Featured on NBC News Regarding Vagal Nerve Stimulation Surgery for Epilepsy

Dr. Kanaly and his patient were interviewed in the “Health Check” Segment of the evening news on Channel 10 NBC on June 13, 2013.  His patient underwent surgery at Memorial Hospital of Rhode Island to implant a vagal nerve stimulator in the neck for treatment of seizures from epilepsy.  Although she had been suffering from seizures for decades, since surgery she has not had a seizure in over 3 months.  Please view the full video below.

NBC 10 Health Check

A summary of the video is available by clicking here.

The news story was featured on the Memorial Hospital website and can be viewed by clicking here.

For more information on vagal nerve stimulation, please click here for an overview and click here for a description of how the therapy works.

Dr. Charles Kanaly Lectured in Providence on Minimally Invasive Options for Back and Leg Pain

Dr. Kanaly gave a free patient education seminar in Providence on minimally invasive options for the treatment of back and leg symptoms.

Dr. Charles W. Kanaly Featured in All Pawtucket All The Time

Dr. Charles W. Kanaly has been featured in an article in All Pawtucket All The Time, a free Pawtucket newspaper. You can read the article here.

Dr. Charles W. Kanaly Featured in My Backyard

Dr. Charles W. Kanaly has been featured in My Backyard, a free Attleboro newspaper & classifieds covering local news from Wrentham to Rumford. You can read the article here. [Read more…]

Dr. Charles W. Kanaly Featured in Three Rhode Island Newspapers

Dr. Charles W. Kanaly has been featured in articles in the Hospital News Rhode Island, Valley Breeze and All Pawtucket All The Time newspapers. The articles cover interviews with Dr. Kanaly and the first patient in Rhode Island to undergo a minimally invasive iO-flex lumbar decompression for lumbar stenosis. You can read the Hospital News Rhode Island article here, the Valley Breeze newspaper article here, and the All Pawtucket All the Time article here.

Dr. Charles W. Kanaly has joined our practice!

RI Neurosurgical is proud to announce that Dr. Charles W. Kanaly has joined our practice!

Dr. Charles W. Kanaly is currently a Clinical Instructor of Neurological Surgery at Boston University School of Medicine and an active member of the Division of Neurosurgery at Roger Williams Medical Center. He graduated summa cum laude from Harvard University with a bachelor’s degree in biology and a certificate in neurobiology. He received his medical degree from Vanderbilt University in Nashville, TN, and then completed his internship in general surgery and his residency in neurological surgery at Duke University Medical Center in North Carolina, which has one of the busiest neurosurgery programs in North America. Dr. Kanaly’s clinical interests include primary and metastatic brain tumors, skull base neurosurgery (including acoustic neuromas, meningiomas, and pituitary tumors), microsurgery for trigeminal neuralgia and hemifacial spasm, minimally-invasive spine surgery, and general adult neurosurgery (including peripheral nerve surgery and spinal cord stimulators).

Another exciting addition to RI Neurosurgical Institute is the pain management program directed by Dr. Sampath and managed by Jorge M. Bonadona, PA-C. Jorge graduated Magna Cum Laude from Massachusetts College of Pharmacy and Health Sciences in Boston with a Master of Physician Assistant Studies degree in 2006. He obtained his Bachelor of Arts degree in Biology from Rhode Island College in 2000.

Jorge started his pain management training at the Handel Center for Spine, Sports, and Rehabilitation in November of 2006.  He joined the RI Neurosurgical Institute in March 2011. His essential role is to provide comprehensive pain management by developing an individualized care plan which may include therapeutic injections, physical therapy, and medication.   He also serves as first assist to Dr. Sampath in the operating room for neurosurgical cases.

Dr. Charles W. Kanaly has Joined the Division of Neurosurgery

Dr. Charles W. Kanaly, a Clinical Instructor of Neurological Surgery at Boston University School of Medicine, has joined the Division of Neurosurgery at Roger Williams. He also joins the practice at Rhode Island Neurosurgical Institute, headed by Dr. Prakash Sampath… [Read the rest in the MedLine Report]

Dr. Kanaly Featured on NBC Channel 10 News

Dr. Kanaly discusses how he is the first and only surgeon in Rhode Island who performs a new minimally invasive technique for the treatment of lumbar stenosis.

For additional information about this surgery, please read our prior news story here.

Please click here to read a pdf of the interview from turnto10.com.

 

Dr. Kanaly performs the first 2 level neck artificial disc replacement in New England

Most patients in the past who have neck surgery for pain, weakness, numbness, or spinal cord compression often receive a fusion. The Mobi-C by LDR has been recently approved as an artificial disc replacement for up to 2 levels, and initial studies suggest that it may be an improvement over neck fusion surgery regarding neck pain, arm pain, increased range of motion, and faster return to work. Xray of the patient is shown below. Please call our office to see if this new minimally invasive surgery option is right for you.

Dr. Kanaly Performs the First Minimally Invasive iO-Flex Lumbar Decompression in Rhode Island

Lumbar stenosis is a common degenerative condition in the lower back that affects over 3 million Americans every year.  It can cause a number of different symptoms, including difficulty walking, lower back pain, or pain, weakness, numbness or tingling in the buttocks and legs. When conservative measures are no longer providing adequate relief, surgery can be very successful in alleviating these symptoms.  The Baxano iO-Flex is an exciting new surgical technique that allows for targeted decompression of the narrowed, degenerated areas while minimizing dissection and disruption of the nearby normal joints and tissue. This minimally-invasive approach may offer improvements in the amount of decompression while minimizing the size of incisions and the amount of normal tissue removal, and possibly even eliminating the need for a fusion surgery. These benefits may therefore improve patient outcomes, including less postoperative pain, less blood loss, and quicker recoveries.

Dr. Kanaly is excited to be the first and only surgeon in Rhode Island to be able to offer this technique to patients, and he performs the procedure at both Memorial Hospital of Rhode Island in Pawtucket, RI and Roger Williams Medical Center in Providence, RI .

Here are the actual x-ray images from the operating room of the first decompression performed with this technique in Rhode Island:

X-ray video

For a brief animation about the specifics of this technique, please watch an animation by clicking here.

Please see Baxano’s YouTube Channel for additional information about this exciting new technique.

Dr. Kanaly’s Treatment of Epilepsy Patients with Vagal Nerve Stimulation is Featured in Local Newspapers

Two Rhode Island newspapers feature articles regarding Dr. Kanaly’s successful treatment of patients with refractory epilepsy using vagal nerve stimulation. Please read the Pawtucket Times article here and the All Pawtucket All the Time article here.

 

Dr. Prakash Sampath is Recognized as a Top Doctor by Rhode Island Monthly

Rhode Island Monthly has released their annual rankings of “Top Doctors” across the state, and Dr. Sampath has once again been honored as a Top Doctor in Neurosurgery.

Please see the full magazine article on their website by clicking here.

Dr. Prakash Sampath Named a Top Doctor by U.S. News & World Report

U.S. News & World Report compiled their list of Top Doctors throughout the United States and included Dr. Prakash Sampath. The determination was based upon recommendations by fellow physicians and then potential candidates were evaluated on their credentials and qualifications by a physician-led research team. Please click here for details on the nomination process.

Dr. Sampath received particular mention of his expertise in the treatment of brain tumors, spine tumors, and surgery of the entire spine. Please see Dr. Sampath’s full listing here.

Featured in Rhode Island Monthly

Dr. Prakash Sampath and Dr. Charles W. Kanaly will be featured in the Physician Profiles section of the upcoming September issue of Rhode Island Monthly Magazine. Look for it in newsstands soon or view the magazine article online (PDF).

Memorial Hospital Advertises Less Invasive Lumbar Decompression Procedure

Dr. Charles Kanaly offers this exciting surgical technique to patients suffering from lumbar stenosis, as described in The Page.

Visit www.mhri.org for additional information or read the pdf here.

 

Memorial Hospital of Rhode Island – Charles Kanaly, MD joins staff

CHARLES KANALY, MD JOINS MEDICAL STAFF
Charles Kanaly, MD, was recently appointed to the Medical Staff in the Department of Surgery / Neurosurgery.

Dr. Kanaly earned his medical degree at Vanderbilt University Medical School, Nashville, TN… Read the rest in The Page

NBC News Affiliates Broadcast Dr. Kanaly’s Interview Across the Nation

Dr. Charles Kanaly is the first and only neurosurgeon in Rhode Island to offer the minimally invasive Baxano iO-Flex lumbar decompression surgery for lumbar stenosis. The news story receives national attention due to the significant benefits that this may offer to patients. Click on the following locations to see their news broadcasts:

KHAS Nebraska Interview

PDF Articles

 

Pictures from Ask the Experts

Dr. Prakash Sampath and Dr. Charles Kanaly joined a panel of distinguished specialists on January 28th at Bethany Home for “Ask the Experts.” This event assisted and educated patients, caregivers and families dealing with brain or spine tumor diagnosis.

View some of the photos from the event below.

 

Radiosurgery Center of Rhode Island website has been updated

The Radiosurgery Center of Rhode Island, of which Dr. Kanaly is an active participant, now has an updated website which can be see here. His bio is featured on a page that can be seen here.

Read Dr. Prakash Sampath’s publication on Interstitial Docetaxel

Interstitial Docetaxel (Taxotere®): a Novel Treatment for Experimental Malignant Glioma

Docetaxel (Taxotere®) is a hemisynthetic, anti-cancer compound with good preclinical and clinical activity in a variety of systemic neoplasms. We tested its activity against malignant gliomas using local delivery methods. Antitumor activity was assessed in vitro against human and rat brain-tumor cell lines. For in vivo evaluation, we incorporated docetaxel into a biodegradable polymer matrix, determined associated toxicity in the rat brain, and measured efficacy at extending survival in a rat model of malignant glioma. Also, we examined the combined local delivery of docetaxel with carmustine (BCNU) against the experimental intracranial glioma. Rats bearing intracranial 9L gliosarcomas were treated 5 days after tumor implantation with various polymers (placebo, 5% docetaxel, 3.8% BCNU, or 5% docetaxel and 3.8% BCNU combination)…. [Read the full publication here]

Research At Brain Tumor Laboratory At The Roger Williams Medical Center

Glioblastoma multiforme is the most common and lethal primary brain tumor. The traditional treatments for GBM, including surgery, radiation, and chemotherapy, only modestly improve patient survival. However, immunotherapy has emerged as a novel therapeutic modality that exploits the patient’s immune system’s ability to recognize and mount a specific response against tumor cells, but sparing normal cells. At the Brain Tumor Laboratory at the Roger Williams Medical Center our interest is targeted immunotherapy for brain tumors.

In pursuit of our interest we have developed “Designer T cells” against malignant glioma. In layman’s term, the T cells that are the immune system’s warrior cells, which are at the forefront of defending the body against any virus attack. The tumor cells, which are really a part of the patient’s own system, outsmart these warrior cells and continue to thrive in the patient’s body. By creating designer T cells, we essentially train the T cells to identify the tumor cells as potential threats, in the same manner by which they identify a virus. The brain tumors or malignant gliomas express a special kind of protein called IL-13 receptor, alpha 2 variant, or in short IL13Rα2, while normal cells of the body express the alpha 1 variant. Both of these proteins interact with a growth-factor protein call Interleukin-13 or in short IL-13. However, IL-13 is fonder of interacting with the normal alpha 1 variant, rather than the alpha 2 variant that are found on the tumor cells. We have developed a mutant-version of the IL-13 that increases its affinity for the rogue alpha 2 variants. What we did next is phenomenal- we engineered the T cells to express the mutant IL-13 on their surface. This procedure retrained the T cells to identify the IL13Rα2-expressing tumor cells as a danger signal and increase their ability to detect and destroy brain tumors. With this special tool, we have been able to successfully cure experimental animals of brain tumors. Our next goal is to take this wonderful technology to the next level of brain tumor therapeutics. Upon sufficient funding and FDA approval, we have plans to start a clinical trial with the brain tumor targeted designer T cells. The Brain Tumor Laboratory at the Roger Williams Medical Center in Providence, RI is headed by Dr. Prakash Sampath, MD, Chief of Neurosurgery and managed by Dr. Sadhak Sengupta, PhD, Instructor of Neurosurgery at the Roger Williams Hospital.

RINI’s Dr. Sampath honored as one of Rhode Island’s Top Doctors for 2012

Rhode Island Monthly magazine has announced the honorees for their 2012 Top Doctor survey. Rhode Island Neurosurgical Institute’s Dr. Sampath has been named to this years honorees.

It’s no secret the physician reimbursement rate in Rhode Island is amongst the lowest in the country. Despite the low payback compared to our neighbors to the north and south, our doctors stay; so in a Rhode Island Monthly survey sent to thousands of the state’s licensed physicians, they asked them why. Their answers? Family, first-rate patients, an invaluable support staff, a love for Rhode Island.

The doctors were also asked to name the specialist they’d choose if a family member or friend had a medical problem. Rhode Island Monthly compiled the names that appeared most frequently on their survey: 161 of the state’s finest doctors, including Dr. Sampath, as voted by their peers.